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For example, a published case report described two patients who developed significant depressive symptoms after starting semaglutide, including one patient with no prior history of depression

Beyond SELECT's findings in people without diabetes, semaglutide has demonstrated cardiovascular benefits across diverse patient populations, including those with type 2 diabetes and varying degrees of heart failure

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The idea is that restoring estrogen levels may support a more favorable metabolic environment, one where appetite-regulating medications can work more effectively