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Additionally, the inducible nitric oxide synthase (iNOS), a crucial enzyme producing Nitric oxide, is expressed in the host neutrophils and epithelial cells ( H

This iron-sequestering capability is particularly important because excess free iron directly enters cells, concentrates in mitochondria, disrupts oxidative phosphorylation, catalyzes lipid peroxidation, and ultimately leads to cell death

The C1-carbon of the bound AsA was 5.0 from Ser20, but rotation of the side chain may produce a suitable distance for catalytic reduction by the Cys20 residue (Fig

This process could cause damage to cells, proteins and DNA