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As shown in Figure 8, Palmatine (degree = 156) has the highest number of targets, followed by columbamine (degree = 143), jatrorrhizine (degree = 109), berberine (degree = 109), corydalmine (degree = 100), tetrahydropalmatine (degree = 99), -sitosterol (degree = 71) and oleanolic acid (degree = 77)

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2.6 Genetic factors Genetic mutations and polymorphisms can elevate the risk of developing neurodegenerative diseases

8 Food lingering in the stomach triggers nausea signals, especially during dose escalation