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Apply 23 drops to clean skin in the evening

Niacin is in the shot as well to reduce tiredness and the onset of fatigue

It is also required for synthesis of nucleic acid, notably DNA, the metabolism of fatty acids and amino acids in the mitochondria, and in delivering SAMe, the universal methyl donor (16) (30)

The frequency of B12 injections varies based on individual needs: For deficiency correction: Injections may be administered more frequently, such as weekly or monthly, until levels normalize. For maintenance: Once adequate levels are achieved, monthly injections are typically recommended

Also, the absence of earlier sampling time points in these studies immediately following antibiotic use may have missed important details that would have provided the authors additional insights