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Studies comparing PRP to corticosteroids found: A randomized trial of 192 patients with knee OA found that PRP provided superior long-term pain relief compared to corticosteroids , with no evidence of cartilage degradation (PMID: 33239706)

Massive effects on gene expression

Shift work as an oxidative stressor

IGF-I LR3 is a recombinant analog of human IGF-I comprised of the complete IGF-I sequence, with an Arginine substitution for the third position Glutamic acid, and a 13 amino acid length N terminus peptide extension

Simmer Cover the pot and let broth simmer on low heat for at least 8 hours for chicken bones and up to 24 hours for beef bones