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The creatine supplementation also promoted energy reserve in the muscle of spotted seabass by increasing ATP concentrations and creatine kinase activity, while inhibiting anaerobic glycolysis by reducing the activities of lactate dehydrogenase and pyruvate kinase [38]

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In still a further embodiment, the Autism Spectrum Disorder (ASD) may comprise autism, Asperger syndrome, pervasive developmental disorder not otherwise specified (PDD-NOS), Childhood Disintegrative Disorder, syndromic autism or autism of known etiology such as fragile X syndrome, PTEN macrocephaly syndrome, RETT syndrome, tuberous sclerosis complex, Timothy syndrome, and/or Joubert syndrome

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