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It is a crucial body response to weight loss, with its main purpose being to prevent starvation

In a clinical trial, adding 2g/day of intravenous choline to TPN for 24 weeks significantly reduced liver fat (measured by CT scans) and improved liver enzymes, while those who continued on unsupplemented TPN showed no improvement.34 When the choline was discontinued, fatty liver returned, underscoring how essential the nutrient is for liver health

[1] It mimics the action of the naturally occurring incretin hormone GLP-1, which is released from the gut in response to food intake

10.3389/fmed.2022.937554 18 DruckerD

Route/evidence mismatch: the pivotal mouse study tested subcutaneous injection at a fixed research dose (20 mg/kg, three times daily) the oral capsule use that is actually sold and discussed commercially has not itself been directly tested in that published research