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The observed biological actions of GHK-Cu are extensive and highly relevant to skin health

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[7] [9] Caution is advised in individuals with renal insufficiency or those on dialysis, as impaired clearance may increase the risk of accumulation and toxicity

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Molecules such as lysophosphatidylcholine acyltransferase-3 (LPCAT3) and long-chain acyl-CoA synthetase 4 (ACSL4) also influence the lipid peroxidation process of membrane PUFAs and aggravating ferroptosis (22)