If your weight remains stagnant despite following your maintenance plan, it may be necessary to reassess your diet, exercise routine, or other factors
The weight loss achieved with GLP-1 therapy appears central to hepatic benefits, as weight reduction of 710% consistently improves NAFLD across multiple intervention studies
Semaglutide, which is the active ingredient in Novo Nordisk's Wegovy and Ozempic, as well as tirzepatide, which is the active ingredient in Eli Lilly's Mounjaro and Zepbound, are considered GLP-1 drugs
In a body composition substudy in people with type 2 diabetes and obesity (PMID: 40609566), retatrutide produced a lean mass loss of about 38% of total weight loss, which falls within the 2040% range reported for other GLP1based therapies such as semaglutide and tirzepatide (see PMID: 40609564
Non-Parenchymal cells and the extracellular matrix in hepatocellular carcinoma in Non-Alcoholic fatty liver disease [J]