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AP-194096), and performed in accordance with the Guidelines for the Care and Use of Laboratory Animals at Kanazawa University

87,88 Sensory deficits include reduced proprioception and vibration sense, leading to numbness and balance difficulties

The use of EGCG and related phenolic compounds can also redirect the amyloid-forming aggregation pathway of transgenic Caenorhabditis elegans strains that express amplified ATX3 (amyloid) toward non-toxic aggregation and prevent calcium influx-mediated cytotoxicity of nerve cells (Visentin et al., 2017)

It is not approved for human or veterinary use and is not intended for clinical administration, therapeutic treatment, or diagnostic procedures