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Hyaluronic Acid and Ceramide deliver intense, lasting moisture to the skin

doi: 10.1155/2015/905215 139 MarquesF

However, some patients receiving high-dose B12 supplementation or injections may experience adverse reactions, though these relate to the treatment rather than the elevated levels: Possible reactions to B12 supplementation (particularly injections): Skin reactions, including acneiform eruptions or rashes Pruritus (itching) Injection site reactions (with parenteral administration) Rare hypersensitivity reactions Non-specific symptoms such as headaches, dizziness, or gastrointestinal disturbances have been reported by some patients taking B12 supplements, but causality is not well established in clinical evidence

Diabetologia (2019) 62(4):66575

However, when ROS and RNS levels become dysregulated, they can cause oxidative damage to lipids, proteins, and DNA, triggering inflammation, impairing synaptic function, and ultimately contributing to neuronal degeneration [368]