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Adjust dosage for patients with hepatic impairment

While oral bioavailability is lower than subcutaneous administration, these studies established that even high oral doses maintained excellent safety profiles, though higher doses (54 mg) were associated with increased gastrointestinal discomfort

According to the results, the elimination half-life (t 1/2 ) of the prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagles at all experimental doses

This may produce hydrolytic cleavage on peptide bonds

How Do GLP-1 Weight Loss Medications Affect Men and Women Differently