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It is recommended over other ergogenic aids because of its demonstrated capacity to boost muscular strength, power, and fat-free mass, all of which improve exercise and athletic performance (173)

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However, individual responses differ substantially based on baseline metabolic status, genetic factors, and medication adherence

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Quick Answer: Blood in stool is not a recognized side effect of tirzepatide, but the medication's gastrointestinal effects may indirectly contribute to conditions causing rectal bleeding that require medical evaluation