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Yes, injections are more effective for people who cannot absorb B12 properly, as they bypass the digestive system and deliver the vitamin directly into the bloodstream

A dietary cause is often managed with daily tablets, or an injection about twice a year

Unfortunately, pain scores were not assessed at any earlier points in this study, it is therefore unknown whether pain had decreased more in the B12 group at an earlier time point

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Seizure medications such as phenytoin and phenobarbital, as well as diabetes medications like metformin, can lower B12 levels over time