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By bolstering fatty acid transport and oxidation, L-carnitine could potentially amplify the fat-burning effects of fasted exercise or extended periods of fasting

These GLP-1 effects include properties such as an anorexic peptide, beneficial cardiovascular actions in humans, increased pulmonary surfactant formation in human and experimental animals, pancreatic islet neogenesis and proliferative and antiapoptotic actions

GABA has been shown to help relieve depression and strengthen immunity, and is largely found in kimchi and yoghurt

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Results from a post hoc subgroup analysis of the SURMOUNT-1 study (NCT04184622), published this year [87] , demonstrated that among 32 pathogenic MC4R variant carriers (1.4% of the study population) with a median age of 41.06 years and a BMI 40 kg/m 2 , treatment with tirzepatide for 72 weeks resulted in an 18.3% reduction in body weight from baseline