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Min, T., et al

It is summarized here for completeness because subsequent work, including Sun et al

Aso M, Toi Y, and Sugisaka J, et al (2020) Association between skin reaction and clinical benefit in patients treated with anti-programmed cell death 1 monotherapy for advanced non-small cell lung cancer Oncologist 25 (3) e536e544 PMID: 32162801 PMCID: 7066688 58

Topical application is the preferred route for cosmetic-adjacent skin research because it delivers the peptide directly to the target tissue while avoiding systemic exposure

6/113) of patients in the high RGC group had an opioid prescription for pain management within 3 months of the GUS assessment compared to the low RGC group (1.0%