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The case series in Medicine specifically highlighted this mechanism, noting that the body water loss associated with GLP-1 agonists may be more significant than commonly appreciated

To mitigate these issues, we finalized a policy in the CY 2019 OPPS/ASC final rule with comment period to utilize our equitable adjustment authority at section 1833(t)(2)(E) of the Act to adjust how we determine the costs for low-volume services assigned to New Technology APCs (83 FR 58892 through 58893)

Currently, there is insufficient high-quality clinical evidence to support its use for IBS symptom management