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Use consistently both morning and night for optimal visible results.Important Notes:For external use only.Discontinue use if irritation occurs and consult a physician.Keep out of reach of children.Store in a cool, dry place away from direct sunlight

Then, these cells were fixed the next day with 4% formaldehyde (Sigma-Aldrich, USA) for 10 min

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Q-switched lasers are particularly effective for dark spots, age spots, and sun-induced pigmentation, making them an excellent choice among melanin reduction treatment options for hyperpigmentation

doi:10.1038/ng1285