glp 1 analogue moa GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes Recent updates on GLP-1 agonists:

This perspective aligns with recommendations from the American Gastroenterological Association Institute Rapid Clinical Practice Update Newsletter, which suggests that implementing a liquid diet on the day preceding sedation or surgery may represent a more acceptable alternative to discontinuing GLP-1RAs therapy185 (See Figure 6)

In clinical practice, even straightforward injectable treatments benefit from sterile technique, proper patient evaluation, and staff trained to recognize and manage adverse reactions

Tirzepatide activates both GLP-1 and GIP receptors, offering a fresh mechanism if semaglutide alone has plateaued

Normal supplement doses do not show negative interactions

These typically subside after a few weeks, especially with gradual dose escalation