3.2.2.1 Curcumin Curcumin, the bioactive compound extracted from turmeric , shows the potent therapeutic effects in various diseases including renal IRI, shock and myocardial ischemia with its antioxidant properties ( via the activation of Nrf2, Sirtuin-1 and Sirtuin-3 ( via inhibiting Keap1, upregulating Nrf2 and inducing the nuclear translocation of Nrf2 ( via Sirtuin-1-Nrf2-ARE signaling pathway ( via Nrf2 to ameliorate mitochondrial oxidative stress, and further restore the activities of renal mitochondrial respiratory enzyme in various kidney diseases ( 3.2.2.2 Resveratrol Besides promoting mitochondrial biogenesis, resveratrol also attenuates mitochondrial dysfunction and restores renal function via other multiple mechanisms
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The samples were analyzed using both full-scan MS and data-dependent MSn scans with dynamic exclusion
Parsons RB, Smith EL, Waring RH, Ramsden DB
Healthy Fats : Incorporate sources of healthy fats like avocados, nuts, and olive oil, which can help reduce inflammation and support overall health