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The before and after results on tirzepatide and before and after results on semaglutide both show this delayed onset followed by accelerating progress

Additionally, using medical and pharmacy claims data can allow health plans and PBMs to more effectively identify patients who are inappropriately prescribed diabetes-approved GLP-1 RAs in the absence of a T2DM diagnosis

A Global Trend, Now Taking Root Locally Internationally, drugs such as semaglutide and tirzepatide have reshaped treatment of type 2 diabetes and obesity, with outcomes surpassing many older regimens

Abstract Aims/hypothesis Whether sodiumglucose co-transporter 2 inhibitors (SGLT2is) or glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are cost-effective based solely on their cardiovascular and kidney benefits is unknown

Physiol Rev