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Glucocorticoids, particularly dexamethasone, promote ferroptosis by activating specific cellular pathways and upregulating dipeptidase-1 expression, consequently depleting GSH levels and enhancing cellular ferroptosis susceptibility [60]

Indeed, a recent study observed a marked inhibition of pro-inflammatory cytokines produced by IL-1-stimulated primary cell cultured human astrocytes when pre/co-treated with WIN55,212-2a synthetic cannabinoid that displays similar effects to THC (Compton et al., 1992

Trials, 20(1), 315