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Understanding IBS Irritable Bowel Syndrome (IBS) is a chronic condition that affects the large intestine, leading to a range of symptoms that can significantly impact an individuals quality of life

This review from Shanghai University of Traditional Chinese Medicine highlights how the #NLRP3 #inflammasome links #MetabolicStress to inflammation, oxidative stress, #pyroptosis, and #fibrosis in #DiabeticCardiomyopathy, and evaluates emerging strategies targeting NLRP3 signaling to break the metabolisminflammation cycle and enable sustained therapeutic remission

Patients are advised to report any unusual numbness, tingling, or coordination problems, as these may signal neurotoxicity if dosing is excessive

Besides the anti-inflammatory effects, omega-3 fatty acids are also involved in transcription factor activity, intracellular signaling pathways, and gene expression (127, 129)

doi: 10.1056/NEJMoa2502081 15 MehtaRGoldenbergRKatselnikDKuritzkyL