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Lactic acid supplementation has been proven to reduce brain damage in hypoxic-ischemic encephalopathy (Roumes et al., 2021)

Another study with CuCl 2 treated Hep G2 cell line demonstrated that mitochondrial toxicity is an intermediate-level event associated with copper toxicity to Hep G2 cells while lysosomal damage is the early event and plasma damage a late feature associated with copper toxicity 34

Moving to an earlier day requires choosing between a small one-time dose compression (option 1) or a larger one-time gap (option 2)

Statistical analysis We analyzed the distribution of these data and applied the F-test to test if the variances of the two populations were equal