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doi: 10.1016/j.ajog.2009.09.002

Based on another study using kainate-induced rat models, PTGS2 expression was elevated in the CA3, cortex, and dentate gyrus regions 1824 h after seizures

doi: 10.1016/j.ejim.2006.04.013 108 MaoucheNMeskineDAlamirBKoceirEA

This is a wide range, and the optimal dose depends entirely on the research goal

Currently, an ongoing phase III, multicenter, randomized, sham-controlled, double-blind trial is evaluating AT-04s efficacy and safety for endometriosis-related pain (dysmenorrhea, dyspareunia, chronic pelvic pain), with the primary outcome being the change in Numeric Rating Scale score at 16 weeks (36)