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2.2.3 Macrophage polarization Macrophage polarization represents a pivotal mechanism in shaping immune responses

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First, rapid dose escalation increases the likelihood and severity of GI side effects, which are particularly problematic for patients with IBD, celiac disease, or other GI-affecting autoimmune conditions

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It also reduces inflammation and improves insulin sensitivity, enhancing the bodys response to insulin, promoting glucose uptake into cells, as well as reducing the risk of associated metabolic complications