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KEGG analysis revealed that neurodegenerative pathways (e.g., Alzheimers disease, Huntingtons disease) were significantly enriched in DM mice, and this enrichment was markedly attenuated by SE treatment (Figures 3C, D)

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After several weeks of training for all study-related procedures, 70 out of 85 monkeys were selected based on blood chemistry and BW data collected at the end of the training period