While the anti-aging implications have not been studied directly in humans, the mechanistic pathway is well-established and suggests potential benefits for anti-aging applications
(Source) When this enzyme is present in great concentration within fat cells and is highly expressed, obesity is inevitable: In the study by Kannt and colleagues, NNMT expression is increased ~2-fold in subcutaneous and omental adipose tissue of type 2 diabetic subjects (men and women), compared to healthy controls Importantly, interventions that increase insulin sensitivity, such as exercise and bariatric surgery, also decreased expression of NNMT in adipose tissue For this reason alone, scientists have been interested in every possible method for inhibiting NNMT expression: We report that NNMT expression is increased in [white adipose tissue (WAT)] and liver of obese and diabetic mice
This article by Peptides Unleashed provides a clear, research-based guide to AOD-9604 , including how it works, recommended dosage protocols, potential benefits, possible side effects, and important safety considerations
The length of time B12 takes to work depends on your age and gut health, and how your body processes the vitamin
Research overview Other vial-size protocols