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[16] These receptors, when activated by allulose, may trigger signalling cascades that promote incretin hormone release, though the magnitude and clinical significance of this effect in humans requires further investigation

Barrera JG, Sandoval DA, D'Alessio DA, Seeley RJ

These medications are contraindicated in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, and are not recommended during pregnancy