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Unlike most other peptides, it doesnt increase systemic growth hormone, making it safer for many patients

Contraindications XIGDUO XR is contraindicated in patients with: Severe renal impairment (eGFR below 30 mL/min/1.73 m2) or end-stage renal disease [see Warnings and Precautions (5.1)]

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There are no direct warnings specifically linking semaglutide to worsening glaucoma, but its impact on eye health should not be overlooked

It is advised to begin with a low dose and increase incrementally