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Subsequent research has demonstrated that the alteration of metabolic pathways and increased metabolism applies universally to all types of macronutrients [24, 114, 115, 117, 118]

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So we really wanted to tackle: if obesity is a disease and we want to treat it as such, like we have other chronic diseases, tell me what the signs and symptoms are of that disease

Metabolic outcomes are similarly mixed but trend favorably when deficiency is corrected, and IR is pronounced