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Serious Side Effects (less common) There can be rare instances of pancreatitis, gallbladder complications, kidney injuries often related to dehydration, serious allergic reactions, vision changes for those with type 2 diabetes, and increased heart rate

Survodutide, one of the drugs presented over the weekend in San Diego, targets both GLP-1 and glucagon receptors

Early Clinical Studies Before the main development program was initiated for the DPP-4 inhibitors, several early clinical studies were undertaken, mainly with vildagliptin and sitagliptin

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