The drug is also being tested in the clinic for another metabolic condition called hypothalamic obesity, which is characterized by uncontrollable weight gain caused by damage to the hypothalamus, the region in the brain that regulates basic bodily functions like appetite, thirst, and sleep
A systematic review of randomized controlled trials found that NAC improved ovulation and pregnancy rates compared to placebo in women with PCOS, though the authors noted variability in study quality.66 More recent meta-analytic research continues to evaluate NAC across both reproductive and metabolic outcomes, suggesting it may offer measurable benefits for some individuals particularly when ovulatory dysfunction and metabolic stress are present.67 You can explore how NAC is used in PCOS research and see our top-rated options in our complete guide to NAC supplements
For patients who have used Berry Street for between 180-365 days, 74% of patients with clinical obesity not on a GLP-1 lost weight, losing 16.9 lbs on average, and 7.3% of body weight
Ongoing research The semaglutide-allodynia connection is an active area of investigation
Studies on semaglutide and weight loss Studies have shown that semaglutide is an effective weight loss drug when combined with diet and exercise