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Unique preclinical characteristic of GG745, a potent dual inhibitor of 5-Rs

DNA methylation is one of the key epigenetic mechanisms for regulation of gene expression which is currently a subject of intensive research and it was reported that maternal deficiency of folate and B 12 could result in aberrant gene expression with consequential health outcomes (Reference Irwin, Pentieva and Cassidy126,Reference Monasso, Hoang and Mancano127)

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10.1111/cns.12655 CNS Neurosci