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At the time of this study, TriNetX Research US Collaborative Network contained EHRs of 105.3 million patients from 61 healthcare organizations, most of which are large academic medical institutions, in the US across 50 states: 25%, 17%, 41%, and 12% in the Northeast, Midwest, South, West, respectively, and 5% unknown region

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Infections: vulvovaginal candidiasis, bacterial vaginosis, vulvovaginitis Comparative observational signal (protective association): In a phenome-wide association study comparing people with type 2 diabetes prescribed GLP-1 receptor agonists vs SGLT2 inhibitors and DPP4 inhibitors (NIH All of Us cohort, Jan 2018Oct 2023), semaglutide prescription was associated with reduced risk of diagnoses including candidiasis of vulva and vagina and inflammatory disease of cervix, vagina, and vulva compared with SGLT2 inhibitors

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Most likely, the mechanism involves stress from rapid weight loss and reduced calorie intake, leading to telogen effluvium