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Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch signaling In a series of studies in our and collaborating laboratories (although predominantly using colorectal cancer-originated tissue and cell lines), we have observed an intriguing inverse correlation between claudin-7 and claudin-1 expressions

The dosage has to be correct to avoid negative implications on the health while achieving the intended results

While studies explore plausible mechanisms (NO-system modulation, VEGFR2-Akt-eNOS signaling, GHR/JAK2 in tendon cells), well-controlled human trials are limited

I mean, I have two more in the can, which are more military-esque and bigger