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Provides targeted neurological protection and anti-aging

Increased levels of NEFAs in the liver are mainly the result of: (i) stimulated lipolysis from visceral fat (hormone-sensitive lipase cannot be sufficiently downregulated)

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CTK solution (0.25% trypsin + 1 mg/mL collagenase IV + 1 mM CaCl 2 + 20% KSR in DPBS ()) was prepared with trypsin ((2.5%), no phenol red, Thermo Fisher Scientific Inc.), collagenase (type IV, powder, Thermo Fisher Scientific Inc.), calcium chloride dihydrate (Fujifilm Wako Pure Chemical Corporation), Knock Out TM Serum Replacement (KSR, Thermo Fisher Scientific Inc.)

Mechanisms and clinical implications of human gut microbiota-drug interactions in the precision medicine era