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Common adverse effects include nausea, vomiting, diarrhoea, constipation, and abdominal pain, which are usually mild to moderate and diminish over time as the dose is gradually increased
Table 1 provides subjects BMI and fasting blood glucose and plasma insulin before and after surgery
17 , sfad285 (2024)
Unpacking the Variables Once the initial loading dose has corrected the severe deficiency, the focus shifts to maintaining healthy B12 levels
For the higher doses (8 mg and 12 mg), additional slower titration cohorts were included to further characterise tolerability
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