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Risks associated with the ownership of infrastructure and infrastructure-related assets include but are not limited to local, national and international economic conditions, supply and demand, the financial condition of users and suppliers of infrastructure assets, changes in interest rates, and changes in environmental laws and regulations

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Higher doses (e.g., 100,000 IU quarterly) should be carefully managed to avoid toxicity

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But as pathogens, toxins, and stress widen those gaps over time (removing the blocks), more and more of those harmful antagonists slip through the barrier