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Interestingly, substituting the amino acids with alanine enhanced the peptides inhibitory ability (Table 1)

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In another study, green tea extracts containing 456 mg of catechins (a type of flavonoid) daily did not have noticeable effects on blood glucose levels or insulin resistance in an RCT lasting for 2 months (153)

Since mitochondria are essential to our very existence, it is unsurprising that the effects of mitochondrial diseases can be severe, and sometimes lethal, spanning a wide-ranging spectrum of physiological and biochemical symptoms [1,3,4] (see Table 1 for examples)