Ipamorelin is a man-made pentapeptide, also known as NNC 26-0161, that is believed to associate with a specific receptor in the pituitary gland cells, termed the growth hormone secretagogue receptor (GHS-R1a)
This profile is consistent with the function of copper as a SOD cofactor and with the observed modulation of antioxidant defense genes Profile observed in models (synthesis): Activity at the level of fibroblasts and extracellular matrix cells stimulation of the synthesis of structural proteins Copper transport function coupled with the activity of Cu-dependent enzymes Modulation of repair and antioxidant gene expression in transcriptomic studies Pro-angiogenic and pro-regenerative profile in wound healing models In research models, GHK-Cu is interpreted as bifunctional extracellular matrix modulator a signal stimulating the synthesis of connective tissue components and a carrier providing copper as a cofactor for enzymes responsible for the maturation and cross-linking of this matrix
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Published research on Ipamorelin is indexed on PubMed
