The injury of renal tubular epithelial cells (RTECs) and epithelial-mesenchymal transition (EMT) are the main causes of renal function decline in DKD patients
In general, mycotoxins affect the physical (intestinal cell proliferation, cell viability, cell apoptosis), chemical (mucins, AMPs), immunological, and microbial barriers of the gut, as reported by Gao et al
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John's Wort : It is sedative, and may cause interactions with other medications and blood pressure changes, prolonging the anesthetic effect