Related to this, it has also been described in vitro that GLO2, using SLG as a substrate, can induce the S-glutathionylation of metabolic enzymes of different cellular compartmentalization, in particular malate dehydrogenase, cytochrome b, and complex I from the mitochondria [12,35,50,51], although the relevance of this observations rests to be determined in vivo
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Genetic and Dermatological Observations Variants in MC1R genes have been associated with variable pigmentation responses in laboratory settings
IF may improve cardiovascular outcomes through various mechanisms