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Multiple delivery routes including oral, transdermal, vaginal, ocular, and nasal have been explored to optimize the therapeutic use of chitosan NPs

This is an essential point to consider when assessing the inter-variability in the response to metformin, as it helps to understand the gut microbiotas contribution to the unresponsiveness

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Lewis cautions that these drugs are relatively new for weight loss, with the first approved in 2014, meaning long-term effects are not yet fully known

It is an essential part of the enzyme SOD, which assists in converting superoxide radicals into less dangerous molecules (150)