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AOD 9604 does not cause fluid retention

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pH Adjustment Techniques : Regularly check the pH levels of your drinking water using testing kits and invest in filtration systems like pH Level Monitoring reverse osmosis system or activated carbon filters to maintain a balanced pH

Put plainly, the off period is not there because the compound stops working it is there because no one can point to human data showing that running it indefinitely is safe, and a scheduled break is the honest way to respect that gap

[1] The American Diabetes Association (ADA) primarily recommends B12 monitoring for patients on long-term metformin therapy rather than for those on GLP-1/GIP receptor agonists