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Studies have investigated potential effects on muscle mass, strength, and exercise capacity in research models

Nerve damage is thought to affect up to half of people with diabetes

More rarely, more serious reactions may occur, such as allergic reactions (urticaria, itching, shortness of breath, facial swelling), heart failure in people with pre-existing problems, or hypokalemia (low potassium levels) at the beginning of treatment due to increased hematopoiesis

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