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This analysis revealed a strong correlation between CDK11 inhibition and SNIP1 depletion (Spearman correlation coefficient = 0.79) providing evidence that CDK11 and SNIP1 affect splicing in a similar manner (Fig

448,449,450 The disturbance of copper metabolism in Wilsons disease is accompanied by an imbalance of iron homeostasis, and anti-copper treatment improves but does not normalize iron metabolism