2 Insulin Resistance and Metabolic Health L-Carnitine has shown promise in treating insulin resistance (IR), with studies indicating its effectiveness in improving the homeostasis model assessment of insulin resistance (HOMA-IR) scores
Systemic inflammatory factors can then enter the CNS, activating microglial NLRP3 inflammasomes
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In atrial tissue, LPS promotes NET release through the activation of inflammatory-immune axes, leading to local microenvironment disruption and contributing to atrial remodeling (Xiang et al., 2024)