In the complex pathogenesis of epilepsy, neuronal apoptosis plays a crucial role, which can be stimulated by abnormally reactive astrocytes induced by cytokine release from activated microglia
SS-31, a mitochondrial-targeted antioxidant, enhances phb2-mediated mitophagy to inhibit mtDNA release, blocking the cGAS-STING pathway and M1 microglial polarization, thereby exerting a neuroprotective effect against POCD [195]
Without proper sleep, you will likely feel unfocused and irritable throughout the day
Almonds: An essential mineral, selenium, works as a cofactor for glutathione and is essential for maintaining glutathione activity in the body
Evaluation of energy expenditure and respiratory quotients (RQ) At day 15 after dosing, the mice were housed individually in the metabolic chamber of the Oxymax system (Columbus Instructions, Columbus, OH, USA) according to the manufacturers instructions