Myers SP, Vigar V
Methionine metabolism requires B6, B12, and folate to prevent homocysteine accumulation, which can cause fatigue and vascular inflammation if elevated
Medical Writing/Editorial Assistance The authors acknowledge the medical writing and editorial assistance of Aislinn Harkin and Beverly La Ferla, of Ashfield MedComms, an Inizio company (funded by Novo Nordisk Inc.)
These may include nausea, vomiting, diarrhea, constipation, abdominal discomfort, decreased appetite, or indigestion
Thus, this modest increase in LDL-C may be misleading regarding ASCVD risk, as patients with obesity may have a higher concentration of atherogenic small, dense LDL particles, and therefore high levels of apoB for a given blood LDL-C [10, 13]